STUDY THE ANTIFIBROUS EFFICACY OF PLANT PROANTHOCYANIDIN IN RATS WITH CHRONIC HELIOTRINE LIVER DAMAGE

Under experimental conditions, the effect of plant proanthocyanidin – yantacin isolated from a camel thorn (Alhagi pseudalhagi) Yantacin, when administered orally at dose 100 mg / kg, on possible changes in early stages liver fibrosis that occurred against background chronic heliotrine hepatitis was studied. The studies were conducted male rats with body weight ±10 g. general and biochemical parameters blood, as well amount NO nitrates (in connection lipoproteins), proteins blood damage At same time, demonstrated significant protective compared to control group detected fibrosis, according which certain indicators, toxic damage. In this regard, more extensive in-depth study studied substance normal impaired activity is carried out.